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Desmethoxy yangonin

CAS No. 15345-89-8

Desmethoxy yangonin( Demethoxyyangonin | 5,6-Dehydrokavain )

Catalog No. M18071 CAS No. 15345-89-8

Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Desmethoxy yangonin
  • Note
    Research use only, not for human use.
  • Brief Description
    Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways.
  • Description
    Desmethoxy yangonin protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. The induction of CYP3A23 by dihydromethysticin and Desmethoxy yangonin involves transcription activation, probably through a PXR-independent or PXR-involved indirect mechanism.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Demethoxyyangonin | 5,6-Dehydrokavain
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Neurological Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    15345-89-8
  • Formula Weight
    228.24
  • Molecular Formula
    C14H12O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 14.29 mg/mL (62.61 mM)
  • SMILES
    COC1=CC(=O)OC(=C1)C=CC2=CC=CC=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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